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In the range of cells affected by the mutation in the GLA gene and contributing to the Fabry disease phenotype, endothelial cells also represent an important part

Potential health benefits of milk thistle Varying degrees of research indicate that milk thistle may offer a fairly broad range of health benefits, principally owing to its radical-scavenging activity

Platelet-secreted chemokine platelet factor 4 (PF4/CXCL4) improves age-related cognitive impairment through hippocampal neurogenesis, which is the key to delaying the aging of the brain

In stark contrast, exogenous lactate administration at moderate doses in experimental settings reveals a protective, pharmacodynamic potential

The availability of software applications to conveniently implement FBA and related in silico methods 20 has enabled the development of genome-scale models (GEMs) for more than 100 species across all three domains of life, thereby facilitating analysis of their intracellular metabolism 21

Effect of treatment on the number and size of bound GTP vesicles and rapid Nrf2 activation in 3xTg-AD hippocampal neurons We hypothesized that impaired vesicular endocytosis was caused by an energy shortage that resulted in a buildup of vesicles and possibly enlargement from failure to complete processing