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doi: 10.1016/j.ijbiomac.2018.11.250 115

As ACSL4 increases PUFA concentrations in cell membranes [21], ACSL4 upregulation has been hypothesized to contribute to the observed lipid peroxidation, morphological changes, and cell death among irradiated cells [20, 35]

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Our examination of tibia tissues shows constitutive adipose tissue is distal regions of both male and female mice from 8-weeks to 71-weeks (Supplementary Figure S1)