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Under the Human Medicines Regulations 2012, selling or supplying either compound with therapeutic claims in the UK without a Marketing Authorisation is illegal

doi: 10.1016/j.bbabio.2008.03.005 21 OjhaRTantrayIRimalSMitraSCheshierSLuBet al

This, in turn, enhances the metabolic rate and activates a gene called SIRT1, often referred to as the longevity gene due to its role in reducing the risk of conditions such as diabetes, obesity, metabolic syndrome, atherosclerosis, kidney disease, liver disease, neurodegeneration, and cancer

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Oral supplements and oral vitamin B12 are also effective methods of supplementation