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The L-type Ca 2+ current, a crucial component of the action potential (AP), is reduced [40] and the action potential duration (APD) is increased in aged cardiomyocytes [Figure 1] [41,42]

Loree JM, Kopetz S

Biochem Biophys Acta 1853:15131527 Qi W, Li J, Chain CY, Pasquevich GA, Pasquevich AF, Cowan JA (2013) Glutathione-complexed iron-sulfur clusters

Once the treatment regimen is completed, the skin may gradually return to its natural shade over time

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In the last few years, cases of successful skin pigmentation resolution with conventional tattoo-removal laser techniques have been reported, offering insight in a promising treatment modality that might revolutionize argyrias natural disease progression and the psychological burden