Yanik, K
The "minimal initial benefit" group (approximately 5-10% of users) reported limited improvements during treatment making discontinuation effects irrelevant, typically explained by inadequate product quality with degraded or low-concentration GHK-Cu, inappropriate application technique reducing absorption, unrealistic expectations exceeding what any topical can achieve, severe underlying pathology requiring medical intervention beyond cosmetic peptides, or individual non-responsiveness to copper peptide treatment for genetic or physiological reasons
The absorbance of D-CuP and M-CuP solutions at 584 nm was measured using a UVVis spectrophotometer
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GHK-Cu is a naturally occurring peptide that binds with copper ions, making it commonly referred to as a copper peptide in research literature