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AOD-9604 enhances the rate and efficiency of fat cell mobilization, but a net caloric deficit is still required for meaningful fat loss

The PNP approach enhances biocompatibility, minimizes immune recognition/adverse effects, prolongs circulation, promotes target site accumulation, and improves therapeutic potential for vascular diseases [70]

Organic oxidants promote mitochondrial lipid peroxidation and ROS accumulation tBHP also induced lipid peroxidation in the mitochondrial fraction as assessed by a mitochondria-targeted fluorescent sensor mitoPeDPP (Fig