melanotic hyperpigmentation Smokers melanosis . Oral pigmentation seen in heavy smokers . Investigations have shown ability of melanin to bind to noxious substances. . Exposure to polycyclic amines ( Nicotine & benzpyrene) has shown Facial frictional melanosis in Indian

Facial frictional melanosis in Indian patients: Defining the entity Semantic Scholar HIVAssociated Oral Mucosal Melanin Hyperpigmentation: A Clinical Study in a South African Population Sample Chandran 2016 AIDS Research and Treatment Wiley Online Library Characteristic peri oral melanotic pigmentation more pronounced on the Download Scientific Diagram Pigmented lesions of the oral mucosa and perioral tissues: a flow chart for the diagnosis and some recommendations for the management ScienceDirect Oral Mucosal Melanosis IntechOpen Oral pigmented lesions: Clinicopathologic features and review of the literature PMC

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