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Our findings indicate that early accumulation of iA, prior to A plaques, is accompanied by incipient oxidative stress and DSBs that may arise directly from oxidative stress or from maladaptive synaptic plasticity

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Moreover, we observed that selenomethionine significantly alleviated cisplatin-induced AKI, as evidenced by reductions in blood urea nitrogen (BUN) and serum creatinine levels (Fig

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3.7 Thyroid and endocrine disruption Thyroid hormones (THs) are critical regulators of neurodevelopment, especially during embryogenesis and early postnatal life [77]

Osmoregulation requires brain expression of the renal Na-K-2Cl cotransporter NKCC2