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Additionally, it controls how the epididymis ducts and seminiferous tubules contract ( It has been shown that exogenous OXY treatment decreases tissue pathology in several animal models (Yuan et al., 2016), and effectively guard against experimental colitis through the AKT/Pi3K pathway ( Interestingly, in light of all the previously described findings, the PCA data demonstrate the extent of testicular damage caused by exposure to LPS, with the toxic group being able to be distinguished from the control or LPS + OXY groups

Acknowledgements We are grateful for the technical support from the members of the Chi lab

[cited 2025 Mar 24]

These may result from other bacteria, viruses, or parasites transmitted by the same tick bite

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Specifically, it inhibits the phosphorylation of Akt at Thr308, leading to subsequent suppression of mTORC1 and mTORC2 signaling cascades