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Despite these advances, critical gaps remain: non-coding RNAs (ncRNAs) such as long non-coding RNAs (lncRNAs), circular RNAs (circRNAs), and microRNAs (miRNAs) have only been sporadically implicated in this network (e.g., miR-125a targeting SLC7A11 in diabetic nephropathy), and their cell type-specific roles in renal ferroptosis remain largely uncharacterized

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It was categorized based on its risk enhancing factor for ASCVD (56)

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Collectively, these alterations impair NPPC proliferative and differentiation capacities, limiting their regenerative potential for IVD repair