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The concentration of GSH can be determined either as an endpoint read of the color developed at 405 nm or by measuring the rate of color development at 405 nm

Overall, glutathiones therapeutic applications with documented outcomes include: (1) chemotherapy neuroprotection (robust RCT evidence), (2) dermatologic pigmentation and skin property modulation (multiple RCTs with modest effects), (3) exploratory use in PD (pilot and ongoing/complete trials), (4) modulation of oxidative stress and immune function biomarkers with formulation-dependent efficacy, and (5) biomarker effects in ASD without symptom data