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The unusual macrocyclic peptides, cyclosporine and voclosporin detailed in Table 1, have much higher oral bioavailability than typical linear peptides

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In terms of experimental design and in order to limit possible confounding effects due to variability between litters or genetic differences across strains, experiments were designed to include animals from multiple litters, typically three independent litters per group and littermate WT animals used as controls 63

In a multivariate analysis of risk factors for disease-specific survival in all patients, age, primary tumor size, and distant metastasis at initial presentation were significant factors, while histological subtype was not

Increased incidence of visceral metastases in Scottish patients with BRCA1/2-defective ovarian cancer: an extension of the ovarian BRCAness phenotype

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