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Effects of SAG on Mitophagy Impairments Induced by CCl4 Chronic Exposure Western blot analysis displayed that the CCl4 induced a decrease in anti-oxidants, including Nrf2 (Figure 4A), HO-1 (Figure 4B) and NQO-1 (Figure 4C), which were restored by treatment with SAG

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H 2 S also enhances NO signaling by increasing NO bioavailability through the inhibition of its degradation and activation of endothelial nitric oxide synthase (eNOS), further elevating cGMP levels and enhancing vasodilation (Cirino and Szabo, 2023)

HPV/E7 induces chemotherapy-mediated tumor suppression by ceramide-dependent mitophagy