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Healthy donor samples were collected under the SingHealth Centralised Institutional Review Board (CIRB Ref: 2017/2806) and HSA Residual Blood Samples for Research project titled Blood biomarkers of immune-related diseases (Ref: #201306-05)

2 Triggers of astrocyte activation in TBI Astrocyte activation in the acute phase following TBI is a complex process initiated by multiple interrelated mechanisms

H., Armitage, M., Allen, J

Raghu, G., Berk, M., Peter, Campochiaro, P

Similar to our previous RNA-seq analysis, we demonstrate that treatment with GLP-1MK-801 significantly regulates around 150 times the number of hypothalamic transcripts relative to the weight-matched semaglutide-treated group, emphasizing a mode of action for GLP-1MK-801 that involves biological pathways independent of the GLP-1 receptor signalling pathway (Fig

These studies utilized classical probiotics ( Lactobacillus and Bifidobacteria ) and FMT illustrating the effect of a targeted and more broad approach to targeting the gut microbiota