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A combination of ALA (50 M) and palmitoyl-ethanolamide (5 M) could reduce OxS (overproduction of ROS and NO) and modulate the major inflammatory cytokines (IL-, IL-6,TNF, and IL-10) involved in COVID-19 infection 534

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The BRAF V600E mutation promotes mitochondrial fatty acid oxidation by activating the ERK/ACC2 phosphorylation axis and releasing the inhibition of carnitine palmitoyltransferase 1 A (CPT1A) [55, 56]

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Noradrenergic inputs from the locus coeruleus suppress I h conductance in MTNs via activation of 2-adrenergic receptors, likely through volume transmission mechanisms (Toyoda et al., 2022)

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