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Although only required in small amounts, it is essential for several enzymatic reactions that are crucial for maintaining good health

Meier-Abt F, Hammann-Hnni A, Stieger B, Ballatori N, Boyer J

This surfeit of electrons further stresses cellular components through oxidative damage resulting in apoptosis or necrosis [21, 22]

doi: 10.1007/s12035-014-8705-x 61 ZelkoINMarianiTJFolzRJ

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In this regard, we did find a modestly elevated thiol content in gsh2 mutant supernatant relative to the WT or complemented strains (Fig