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Batiha GE, Al-Kuraishy HM, Al-Gareeb AI, Elekhnawy E (2022) SIRT1 pathway in Parkinsons disease: a faraway snapshot but so close

In addition, FX11 decreased the IL-1 expression in bFLS (Fig

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It provides a logical explanation for the development of dual targeting drugs such as MM-131 a bispecific anti-MET/EpCAM mAb [108] and also further drug discoveries targeting concurrently all three c-Met, EpCAm and Wnt pathway simultaneously to overcome both innate and acquired resistance to tyrosin kinase inhibitors (TKIs)

Given that global or neural-specific GLUT3 knockout models result in embryonic lethality or neurobehavioral abnormalities 82,83,84 , we used a GLUT3 KD approach in N41 cells to investigate its functional role