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This is an enzyme family which hydrolyses glycerophospholipids to produce free fatty acids and lysophospholipids, both of which serve as precursors in the production of signaling molecules and second messengers of inflammatory processes such as eicosanoids and diacylglycerol

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For example, neutrophils in the inflamed tissues produce large amounts of ROS, which can suppress or even kill T cells

Sohail M, Urooj Z, Noreen S, Baig M, Zhang X, Li B

Although the topic is of great interest, the manuscript tends to be a bit chaotic at times and arguments made in the manuscript do not always appear to follow from cited work