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encapsulated quercetin in PLGA nanoparticles and found that this nanodelivery system exhibited stronger cardioprotective effects against oxidative stress compared with free quercetin, especially by reducing mitochondrial ROS production, maintaining mitochondrial function and preserving ATP synthesis (Lozano et al., 2019)

doi: 10.2478/jtim-2023-0099 185 MaoCWangMZhuangLGanB

The effectiveness of footwear and offloading interventions to prevent and heal foot ulcers and reduce plantar pressure in diabetes: a systematic review