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Polydopamine-based resveratrol-hyaluronidase nanomedicine inhibited pancreatic cancer cell invasive phenotype in hyaluronic acid enrichment tumor sphere model

Baraka M, Alghamdi M, Alahmari A, Alghamdi A, Alfayez A

Maddocks, O.D., et al., Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells

Invasive delivery methods (e.g., intracerebral infusion or convection-enhanced delivery) improve local concentrations but introduce risks of hemorrhage, infection, and inconsistent distribution across the extensive dopaminergic axonal network

doi: 10.1021/np0100800

Eventually, macrophages and extracellular protein-hydrolyzing enzymes remove clots and tissue debris to complete the repair process [164]