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Mathews-Roth MM, Pathak MA, Fitzpatrick TB, Harber LH, Kass EH

Blood was obtained via tail nick using a sterile blade

Microglial activation induces nitric oxide signalling and alters protein S-nitrosylation patterns in extracellular vesicles

Those are two completely different contexts, patients, and purposes one has nothing to do with the other, and the chemo dose is not something to replicate for cosmetic reasons