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Effect of downregulation of survivin expression on radiosensitivity of human epidermoid carcinoma cells

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El-Mancy et al

28 Under BSO treatment, genes related to lipid metabolism and ferroptosis were essential in GshF- expressing cells, which may indicate that having lower mitochondrial GSH levels may sensitize cells to lipid peroxides in the mitochondria (Fig

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Low glutathione levels have been linked to abnormalities in the lungs' lining, and having normal glutathione levels may protect from inflammation by protecting lung tissue from free radical damage.27 Additionally, animal studies found that intravenous glutathione supplementation helped maintain normal lung function and prevent damage such as decreased lung compliance, increased swelling, and reduced lung tissue