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Artesunate inhibited the proliferation of HFL-I cells in a time- and concentration-dependent manner, and apoptotic cells were seen after staining with Hochst33258

Common Characteristics of SABAs Metered Dose Inhaler (MDI) & nebulizer inhalable formulations Rapid acting (1-5 minutes) Half lives of 6 hours or less Fewer systemic effects (compared to systemic administration) Significantly increases the one second forced expiratory volume in the forced vital capacity test (FEV1) Commonly Used SABAs Albuterol (ProAir, Ventolin, Proventil ) Levalbuterol (Xopenex ) - the R isomer of albuterol Metaproterenol (Alupent ) - liquid taken by mouth or for use in nebulizers Pirbuterol (Maxair ) Figure 7

10.1371/journal.pone.0157855 89 JonesS