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Biosci Biotechnol Biochem 72:30383040

Rangel-Huerta et al

Keap1 has a suppressing role on Nrf2 [86], and it is the key negative regulator of Nrf2 [87]

Nature (2013) 496:44555

In clinical practice, the efficacy of using antioxidants alone to treat ED is limited, and they are often used as complementary and alternative therapies in ED patients