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Wash three times the platelets with 1 ml PBS containing 2 mM NEM and, after the third washing, discard the supernatant and add 1 ml of 3% (w/v) TCA

Toxic metals and oxidative stress part I: mechanisms involved in metal-induced oxidative damage

Redox signaling in rheumatoid arthritis and the preventive role of polyphenols

In this process, the molecules NADH and FADH 2 - derived from the TCA cycle or from the OXPHOS cycle of fatty acid metabolism - are oxidized and thereby function as electron donors in a series of redox reactions (also referred to as the electron transport chain) with oxygen as ultimate electron acceptor (Mehta et al., 2017

Melatonin interacts with its membrane receptors, activating cascades of intracellular signals that regulate the transcription factors of key enzymes that act in the processes of cancer development, altering DNA and generating changes in cancer cells and their microenvironment, reducing carcinogenic development [28,33]