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Due to their ability to adapt to the harsh, nutrient-poor IVD microenvironr potential to effectively differentiate into NP-like cells, NPPCs have emerged as a promising candidate for cell-based regenerative therapies aimed at IVD repair

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pre, pre-treatment

If we think about it, we didn't get to choose our eye color

Upon activation, HSF1 trimers translocate to the nucleus and bind to heat shock elements (HSEs) in the promoters of target genes, thereby increasing the transcription of HSP70s, which then undergo degradation or re-monomerization (Vihervaara and Sistonen, 2014)