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Effect of increasing dietary fiber on plasma levels of colon-derived solutes in hemodialysis patients

10.1002/ar.24378 191 ShimadaK.SkoutaR.KaplanA.YangW

Also, metabolites of VPA -oxidation (including propionic derivatives and 4-en-VPA) inhibit the mitochondrial CPS I, which is the first enzyme necessary for ammonia elimination via the urea cycle in the liver [19, 24]