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Moreover, up-expression of GSTA was suggested to protect liver cells against oxidative stress via an extracellular signal-regulated kinases (ERKs) and p38 kinase (p38K)-related pathway, as well as through the inhibition of H2O2-induced apoptosis to inhibit reactive oxygen species (ROS)- induced lipid peroxidation

1 In addition, the results presented strongly support the view that mitochondrial GSH play essential roles for mediating ISC biogenesis as opposed to redox buffering

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Oxidative stress can lead to lipid peroxidation, a process in which ROS react with lipids in cell membranes, resulting in the formation of lipid peroxides and aldehydes such as malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE) [9]

It has also been shown that EC-SOD plays an important role in reversing the chronic, progressive form of pulmonary arterial hypertension (Lopez et al

Some patients may be able to benefit from weekly sessions, while others might require treatments only once a month