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View Abstract Respiratory, neuromuscular, and cardiovascular effects of neosaxitoxin in isoflurane-anesthetized sheep

63 The accumulated NAPQI depletes GSH in the endoplasmic reticulum to induce an oxidationreduction imbalance, which initiates the phosphorylation of eukaryotic initiation factor 2 (eIF2) to activate ATF6 and CHOP, eventually resulting in hepatocyte apoptosis (Figure 2)

Mol Biol 53:696703

MessaECarturanSMaffCPautassoMBraccoERoettoAet al

Twice-weekly sessions during the first month tend to accelerate early progress

The thyroid gland, a butterfly-shaped organ located at the base of the neck, is responsible for producing hormones critical to regulating metabolism, growth, and development [8]