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Association for the Study of the Liver

We hypothesised that the telomere length elongation seen in the cancer cell lines may be due to ALT activity

It could be speculated that the altered methylation status of this gene, as opposed to Gnrh or Kiss1 , might be subtle enough for the reproductive system both to sense and tolerate without implementing compensatory mechanisms to overcome it, allowing SRD5A1 to function in this context