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In the majority of cell lines, a 50% reduction can be achieved with no weaning procedure

In parallel, they exert significant immunomodulatory effects: polysaccharides stimulate the immune system's antitumor response by activating macrophages, T lymphocytes, natural killer cells, and dendritic cells, and by promoting the release of cytokines such as TNF-, IFN-, and IL-2 (134)

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10.1016/j.mam.2013.06.001 62

Semax, a synthetic analogue of the adrenocorticotropic hormone, rapidly elevates brain-derived neurotrophic factor (BDNF) levels, promoting the growth and differentiation of new neurons and synapses in critical brain regions