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To quantify reporter expression mice were perfused with artificial cerebral spinal fluid, followed by perfusion with 15 ml of 4% formaldehyde solution

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This action removes two fibrinopeptides, exposing knobs and holes, and leading to a remarkable self-assembly in which fibrin monomers polymerise to make staggered oligomers, which themselves lengthen into protofibrils that aggregate laterally to make fibres, finally branching to create a three-dimensional network which represents the clots

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Dig Dis Sci 54:20702083 Sikiric P, Seiwerth S, Rucman R, Turkovic B, Rokotov D, Brcic L, Sever M, Klicek R, Radic B, Drmic D, Ilic S, Kolenc D, Aralica G, Stupnisek M, Suran J, Barisic I, Dzidic S, Vrcic H, Sebecic B (2014) Stable gastric pentadecapeptide BPC 157-NO-system relation