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10.1016/j.jaci.2016.10.013 88 LiangC.ZhangX.YangM.DongX

Cancer 67 (1), 126136

Absent in melanoma 2-like receptors (ALRs) By detecting dsDNA in the cytoplasm of cells, the pyrin and HIN domain-containing missing in melanoma 2 (AIM2) protein functions as a potent activator of the inflammasome to trigger IL-1 and IL-18 secretions