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Furthermore, inhibition of IDH1 in CCNE1-driven tumours in vivo decreased the abundance of KG, l-carnitine, and acetylcarnitine (Fig

As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day

Since aerobic glycolysis represents a hallmark of metabolic reprogramming that sustains tumor growth 37 , these results highlight a previously unrecognized metabolic role of MAT2A in OS