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Thus, the combined therapy of two kinds of antibodies is beneficial to MM patients, especially those who received anti-PD-1/PD-L1 antibodies and developed acquired resistance [114, 116]

reported that DHA and EPA reduced cholesterol synthesis in the chemoresistant HT29-dx colon cancer cells even at concentrations as low as 50 M

49 Furthermore, the constitutive expression of claudin-1 in gut epithelium in mice resulted in decreased claudin-7 expression and enhanced susceptibility to acute colitis

Hepatic glucagon receptor activation stimulates fatty-acid oxidation, reduces hepatic steatosis, and most importantly raises resting energy expenditure

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