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The common flavones, isoflavones, flavanols, dihydroflavones, dihydroflavonols, anthocyanidins and chalcones, as part of the daily diet, imparts health benefits such as antioxidant, anticancer, antiinflammatory, and antihepatic fibrosis properties, which is a better choice for development as a therapeutic liver

doi: 10.1016/S1474-4422(13)70210-2 289 Vande VeldeC.McDonaldK

Elevated TREM2 gene dosage reprograms microglia responsivity and ameliorates pathological phenotypes in Alzheimer's disease models

Interestingly, a normal intestinal microbe ( Lactobacillus rhamnosus GG) was able to be co-cultured with the intestinal cells on the luminal surface for more than 1 week using this gut-on-a-chip

However, small donor sample sizes limit generalizability, as they may not capture donor-dependent shifts or reflect broader diversity in age, diet, or health

Lazarow PB, De Duve C (1973) The synthesis and turnover of rat liver peroxisomes