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In dogs under physiologic strain, oxidative stress can be higher, which is where antioxidant support may be considered

Additionally, redox-sensitive transcription factors such as NF-B and AP-1 are persistently activated, driving the expression of pro-inflammatory cytokines (e.g., TNF-, IL-1) and MMPs that degrade the already-compromised ECM (Connizzo et al., 2014)

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rs72613567 variant in HSD17B13 is an insertion mutation, wherein the Adenine nucleotide gets incorporated next to thymine present at the donor splice site of exon 6 (TTA)

This dimensionality reduction underscores the importance of precise model scaling, with the 128-dimensional representation striking an optimal balance between performance and computational efficiency