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Although oxidative damage in biological systems has in the past been completely attributed to ROS, it is becoming increasingly clear that also reactive nitrogen species (RNS) and reactive sulfur species (RSS) are integral components of signal transduction processes in cells, and play important roles in OS generation [2, 25, 35]

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Sterile supernatants (obtained by filtering through a 0.22 m microbial filter) of L

We first confirmed that the addition of alkyne handles to SCLA1-4 did not ablate senolytic activity (Extended Data Fig

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