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Many cancer cells adapt to stressful conditions by upregulating stress-buffering proteins such as glucose-regulated protein 78 (GRP78), 158 which dampens ER stress signaling, or activating nuclear factor erythroid 2related factor 2 (Nrf2)-mediated antioxidant pathways to suppress ROS accumulation, 159 thereby blunting DAMP release even in response to ICD-inducing agents

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However, some patients will go to great lengths to continue using topical anesthetics despite the damage

and to inhibit the damaging effects of UV radiation from sunlight

It regulates fat metabolism, preventing unwanted fat accumulation and aiding in healthy weight loss