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When using Hydrocodone Bitartrate and Acetaminophen Tablets with CYP3A4 inducers or discontinuing CYP3A4 inhibitors, follow patients at frequent intervals and consider increasing the opioid dosage if needed to maintain adequate analgesia or if symptoms of opioid withdrawal occur [see PRECAUTIONS

doi: 10.1111/ijlh.12500 16

Citrinin (CTN) The DUST Test Analytes Group 1: Water Damage Indicator Molds (26 Species) Aspergillus flavus/oryzae Aspergillus fumigatus Aspergillus niger/awamori/foetidus/phoenicis Aspergillus ochraceus/ostianus Aspergillus penicillioides Aspergillus restrictus/caesillus/conicus Aspergillus sclerotiorum Aspergillus sydowii Aspergillus unguis Aspergillus versicolor Aureobasidium pullulans Chaetomium globosum Cladosporium sphaerospermum Eurotium (Aspergillus) amstelodami group Paecilomyces variotii Penicillium brevicompactum Penicillium corylophilum Penicillium crustosum Penicillium purpurogenum Penicillium spinulosum Penicillium variabile Scopulariopsis brevicaulis/fusca Scopulariopsis chartarum Stachybotrys chartarum Trichoderma viride Wallemia sebi Group 2: Common Indoor Molds (10 Species) Acremonium strictum Alternaria alternata Aspergillus ustus Cladosporium cladosporioides 1 Cladosporium cladosporioides 2 Cladosporium herbarum Epicoccum nigrum Mucor/Rhizopus Penicillium chrysogenum Rhizopus stolonifer Exposure to CTN has been linked to the development of nephropathy, which is caused by CTNs ability to increase the permeability of mitochondrial membranes in the kidneys

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Flohe L, Gunzler WA, Schock HH