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Description

Findings on Bone and Joint Pathways Fragment 176-191 has been studied with hyaluronic acid in models of osteoarthritis, where it appeared to be linked with cartilage integrity

Benefits Direct activation of the IGF-1 receptor for anabolic signaling: IGF-1 LR3 binds directly to the IGF-1 receptor expressed on muscle and other peripheral tissues

CJC-1295 is a growth hormone-releasing hormone (GHRH) analogue that extends the duration of GH pulses by preventing enzymatic degradation

Supplementary Figs

Effect of intra-articular injection of AOD9604 with or without hyaluronic acid in rabbit osteoarthritis model

Preclinical studies corroborate that Golgi stabilization effectively reduces pro-ferroptotic membrane lipid composition, suppresses ferroptosis, and alleviates airway inflammation, validating this organelle as a promising target for therapeutic intervention