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The use of A42H13L (TABLE 1), in which one of the adjacent His residues was replaced by Leu, a substitution that would preclude any bidentate Cu 2+ ligand binding, led to results consistent with the notion that bidentate Cu 2+ ligand binding of these His residues was not essential for the oxidative damage and cellular toxicity of the native peptide (115)

doi: 10.1016/J.IJANTIMICAG.2014.04.020 46 DunnM

Barrett P, Glennon B

Conclusion: Optimizing Your Vitamin B12 Therapy Understanding the right dosage and how to get it is key to good vitamin B12 therapy

A more stringent mitochondrial content threshold of 5% was applied to the data, but all the remaining filters of the pipeline were disabled because the data had already been filtered

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