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64-65.] Leibovitz and Siegel state: However, as free radicals (FR) steal an electron from the other molecules, they convert these molecules into FRs, or break down or alter their chemical structure

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Therefore, our finding that SFN has an immunosuppressive effect on untransformed human T-cells may explain why treatment with SFN did not lead to amelioration of cancer severity in patients as demonstrated in a number of clinical trials ( in vitro experiments on tumor cells such as breast cancer cell and hepatocellular carcinoma cell strongly suggested that SFN has anti-tumor properties (63)

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