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2014 Mar;33(1):70-3

Dont forget electrolytes: FAQs How can I calculate my body`s hydration needs

Many people notice improvements in energy and symptoms within days to weeks, but this can vary

For example, certain drugs that treat multiple sclerosis or rheumatoid arthritis may require self-injection

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One explanation for this modest effectiveness is that most cancer patients are elderly, frail and cannot tolerate high doses, in contrast to relatively healthy tumour-bearing mice that can be given higher doses [85]