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Whole-body caveolin 1 knockout (c av1 / ) reduced hepatic steatosis in high fat fed mice in response to 24 h of fasting, whereas liver-specific caveolin 1 knockout did not affect hepatic fat content [29]

Accordingly, agents that restore glutathione-glutamate homeostasis may afford therapeutic benefit

SKP2 acetylation, which is critical for its cytoplasmic retention and stabilization, is deacetylated by SIRT3 (refs

Epub 2013 Dec 24

The autophagy inhibitors CQ and HCQ decrease the autophagy process in glioma cells exposed to TMZ, causing an accumulation of proautophagy proteins and strain on the endoplasmic reticulum [262]

Randaccio L, Geremia S, Demitri N, Wuerges J