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Therefore, the risk of AAD formation can be assessed clinically by detecting the levels of corresponding metabolites in plasma or serum

96 The iron from lysosomes appears to be taken up into mitochondria, contributing alongside ROS to the opening of the MPTP and subsequent cell death

CacciapuotiSAnnunziataMCMegnaMVillaniAMartoraFFabbrociniGet al

This is particularly important for essential and abundant proteins whose overoxidation would lead to loss of cell viability and requires new protein synthesis to replace inactivated proteins

Pyridoxamine improves survival and limits cardiac dysfunction after MI