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Lidocaine with epinephrine is typically given by a healthcare professional just prior to a procedure

They go directly into the bloodstream and begin working almost immediately

17 Parry-Strong, A., Langdana, F., Haeusler, S., Weatherall, M

The major bottlenecks for this therapy include ensuring long-term survival, functional integration of transplanted mitochondria into host cells, and development of standardized, scalable protocols for mitochondrial isolation and delivery