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Factors such as a poor diet, environmental pollutants, and the natural process of aging can deplete our stores

Step-by-step: 1) Collect genetics and baseline labs

For example, in mouse embryonic stem cells, excess 2-OG maintains pluripotency dependent on the 2-OG/succinate ratio by increasing TET and KDM activity 45

Kuhn V, Diederich L, Keller STC IV, Kramer CM, Lckstdt W, Panknin C, Suvorava T, Isakson BE, Kelm M, Cortese-Krott MM (2017) Red blood cell function and dysfunction: redox regulation, nitric oxide metabolism, Anemia

This can affect the absorption timing of any oral medication