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Routine screening of B12 status

Clinical Benefits Reduces intestinal inflammation and helps manage symptoms associated with IBD, IBS, Crohns disease, and ulcerative colitis through direct anti-inflammatory action

It also appears to decrease ectopic nerve firing, which could explain why it helps alleviate painful symptoms 12 Earlier studies show that high-dose vitamin B12 promotes neurite outgrowth and neuronal survival, as well as increasing extracellular signal-regulated kinases and Akt signaling after sciatic nerve injury

Am J Gastroenterol 1977

1 Chemotherapy alone or combined with surgery/radiotherapy plays an important role in improving the life expectancy of cancer patients

Your GP will explore: Dietary history (particularly relevant for vegans and vegetarians) Gastrointestinal symptoms suggesting malabsorption Medication history (metformin, proton pump inhibitors, and H2-receptor antagonists can impair B12 absorption) [17] [9] Previous gastric surgery Family history of pernicious anaemia Important : If neurological symptoms are present, treatment should be started immediately without waiting for test results