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Il joue un rle essentiel dans la cicatrisation, langiogense et le remodelage cellulaire, et il est largement tudi pour son influence sur la synthse du collagne, la signalisation anti-inflammatoire et lexpression des gnes associs la rparation cutane et des organes

Furthermore, it has been demonstrated that p53 exerts a direct inhibitory effect on DPP4 in a transcription-independent fashion, thereby impeding the occurrence of ferroptosis (Xie et al., 2017

Kaya Aygnolu S, elebi A, Vardar N, Grsoy E

The Spread of Tumours in the Human Body 3rd edn (Butterworths, 1973)

As a ferroptosis resistance factor, FSP1 compensates for GPX4 deletion by mediating the reduction of oxidized coenzyme Q to ubiquinol, a lipophilic antioxidant, thereby preventing the propagation of lipid peroxidation [76, 77]

Enhancing autophagy (e.g., through mTORC1 inhibitors, AMPK agonists, or TFEB activators) may indirectly reduce hepatic inflammation by improving lipid metabolism